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EC number: 235-227-6 | CAS number: 12136-45-7
- Life Cycle description
- Uses advised against
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- Appearance / physical state / colour
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- Boiling point
- Density
- Particle size distribution (Granulometry)
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- Water solubility
- Solubility in organic solvents / fat solubility
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- Flash point
- Auto flammability
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- Explosiveness
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- Stability in organic solvents and identity of relevant degradation products
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- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
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- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
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- Nanomaterial pour density
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- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
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- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
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- Genetic toxicity
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- Specific investigations
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- Additional toxicological data

Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to soil macroorganisms except arthropods: long-term
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QSAR prediction: S EPA accepted QSAR method for chemicals properties assessment.
- Qualifier:
- according to guideline
- Guideline:
- other: QSAR
- Principles of method if other than guideline:
- ECOSAR Program (v1.00)
- GLP compliance:
- no
- Remarks:
- not applicable to QSAR models
- Analytical monitoring:
- no
- Vehicle:
- no
- Test organisms (species):
- other: earthworm
- Animal group:
- other: QSAR model
- Study type:
- other: QSAR
- Substrate type:
- other: QSAR
- Limit test:
- no
- Total exposure duration:
- 14 d
- Test temperature:
- not applicable. QSAR model
- pH:
- not applicable. QSAR model
- Moisture:
- not applicable. QSAR model
- Details on test conditions:
- -Name of test material (as cited in study report:Potassium oxide
CAS Number: 12136-45-7
SMILES : KOK
CHEM : Potash (potassium oxide)
MOL FOR: O1 K2
MOL WT : 94.20
Wat Sol: 1E+006 (mg/L, EPISuite WSKowwin v1.43 Estimate) - Reference substance (positive control):
- no
- Duration:
- 14 d
- Dose descriptor:
- LC50
- Effect conc.:
- 887.517 mg/kg soil ww
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
- Remarks on result:
- other: 1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
- Details on results:
- LC50 (14-day, earthworm)= 887.517 mg/L (ppm)
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
LC50 (14-day, earthworm)= 887.517 mg/kg soil dw - Reported statistics and error estimates:
- US EPA accepted QSAR method for chemicals properties assessment.
- Validity criteria fulfilled:
- yes
- Remarks:
- US EPA accepted QSAR method for chemicals properties assessment.
- Conclusions:
- LC50 (14-day, earthworm)= 887.517 mg/L (ppm)
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
LC50 (14-day, earthworm)= 887.517 mg/kg soil dw - Executive summary:
The ECOSAR QSAR model predicts that 14-day, LC50 (14-day, earthworm) would to be 887.517 mg/L (ppm).
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
LC50 (14-day, earthworm)= 887.517 mg/kg soil dw
- Endpoint:
- toxicity to soil macroorganisms except arthropods: long-term
- Type of information:
- other: Published data
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Test substance was added to fresh pine litter substrate. pH and conductivity was measured during 6 months. At regular times the enchytraeids are counted both in the controls and in the test samples. Toxicity was estimated by calcuting the regression equation between reproduction number and pH or conductivity.
- GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Details on sampling:
- - Concentrations: 0, 500, 1000, 1500, 2000, 2500, 3000, 3500, 4000, 4500, 5000 mg/l
- Vehicle:
- no
- Test organisms (species):
- Enchytraeus sp.
- Animal group:
- annelids
- Details on test organisms:
- TEST ORGANISM
- Source: Rijksuniversiteit Gent - Study type:
- laboratory study
- Substrate type:
- artificial soil
- Limit test:
- no
- Total exposure duration:
- 180 d
- pH:
- 7.3 (init.) - 6.3 (fin.)
- Moisture:
- humidity was adjusted weekly with rainwater
- Details on test conditions:
- TEST SYSTEM
- Amount of soil or substrate: 3 g/l
- No. of replicates per treatment group:4
SOURCE AND PROPERTIES OF SUBSTRATE (if soil)
-Composition (if artificial substrate): fresh pine substrate
- pH=4.4
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : reproduction - Nominal and measured concentrations:
- - Nominal concentrations: 0, 500, 1000, 1500, 2000, 2500, 3000, 3500, 4000, 4500, 5000 mg/l
- Reference substance (positive control):
- not specified
- Duration:
- 180 d
- Dose descriptor:
- EC50
- Effect conc.:
- 850 other: mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- other: population density
- Duration:
- 180 d
- Dose descriptor:
- other: EC92
- Effect conc.:
- 3 000 other: mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- other: population density
- Details on results:
- The values of EC50 and EC92 are calculated using the regression given in the method. The enchytraeid population was >95% Cognetia sphagnetorum.
- Validity criteria fulfilled:
- not specified
- Conclusions:
- 180d EC50 = 850 and EC92 = 3000 mg/l for the enchytraeid population in fresh pine substrate.
When Potassium oxide is hydrated is produced Potassium hydroxide. Therefore, the health effects of Potassium hydroxide need to be considered in the assessment of Potassium oxide
Referenceopen allclose all
Overview of QSARs estimations on toxicity of Dipotassium oxide/Potassium oxide to soil macroorganisms
Method
|
Results |
Remarks |
Reference |
QSAR estimate |
LC50 (14-day, earthworm)= 887.517mg/L (ppm)
|
Reliable withrestrictions, QSAR estimated data |
ECOSAR Program (v1.00) |
LC50 (14-day, earthworm)= 887.517 mg/kg soil dw
The values of EC50 and EC92 are calculated using the regression given in the method. The enchytraeid population was >95% Cognetia sphagnetorum.
Description of key information
180d LE50 = 850 and EC92 = 3000 mg/l for the enchytraeid population in fresh pine substrate.
The ECOSAR QSAR model predicts that 14-day, LC50 (14-day, earthworm) would to be 887.517 mg/L (ppm).
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
LC50 (14-day, earthworm)= 887.517 mg/kg soil dw
Key value for chemical safety assessment
- Short-term EC50 or LC50 for soil macroorganisms:
- 850 mg/kg soil dw
- Long-term EC10, LC10 or NOEC for soil macroorganisms:
- 170 mg/kg soil dw
Additional information
180d EC50 = 850 and EC92 = 3000 mg/l for the enchytraeid population in fresh pine substrate.
The ECOSAR QSAR model predicts that 14-day, LC50 (14-day, earthworm) would to be 887.517 mg/L (ppm).
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
LC50 (14-day, earthworm)= 887.517 mg/kg soil dw
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