Registration Dossier

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only insufficient documents about study available and documentation/performance of study insufficient.
Cross-referenceopen allclose all
Reason / purpose:
reference to same study
Reason / purpose:
reference to other study

Data source

Reference
Reference Type:
publication
Title:
No information
Author:
Moutschen-Dahmen J et al
Year:
1976
Bibliographic source:
Bull Soc r Liege, 45, 58-72

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
No indication of methods sued.
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
No information provided

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified
Details on test animals and environmental conditions:
No information provided

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified
Details on exposure:
No information provided
Doses:
No information provided
No. of animals per sex per dose:
No information provided
Control animals:
not specified
Details on study design:
No information provided
Statistics:
No information provided

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
1 140 mg/kg bw
Based on:
test mat.
Mortality:
No information provided
Clinical signs:
No information provided
Body weight:
No information provided
Gross pathology:
No information provided
Other findings:
No additional information

Any other information on results incl. tables

No information provided

Applicant's summary and conclusion

Conclusions:
The results of this study indicate an LD50 of 1140 mg/kg bw
Executive summary:

In the study conducted by Moutsche-Dahmen (1976), the mouse was administered the test substance by intraperitoneal injection. The results of this study indicate an LD50 of approximately 1140 mg/kg bw/