Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-646-6 | CAS number: 123-72-8
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1986
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Comparable to guideline study, confidence level significantly enhanced through comparison with other included chemicals. Also mentioned in OECD SIDS
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 986
- Reference Type:
- publication
- Title:
- A method to classify biodegradabilities of organic compounds
- Author:
- Urano K, Kato Z
- Year:
- 1 986
- Bibliographic source:
- J Hazardous Materials 13, 135-145
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- Deviations:
- yes
- Remarks:
- Duration =<14 d; evaluation/rating system different from standard criteria of today
- Principles of method if other than guideline:
- Respirometry Test (BOD of ThOD);
Electrolytic respirometer containing 30 mg/l activated sludge over a 14-day period at 20°C - GLP compliance:
- no
Test material
- Reference substance name:
- Butyraldehyde
- EC Number:
- 204-646-6
- EC Name:
- Butyraldehyde
- Cas Number:
- 123-72-8
- Molecular formula:
- C4H8O
- IUPAC Name:
- butanal
- Details on test material:
- No data
1
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
Not relevant
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- concentration in test apparatus: 30 mg/L
- Duration of test (contact time):
- <= 14 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Electrolytic respirometer;
pH of solution: 7 +/- 1;
culture mediums: JIS inorganic mediums, 1 mL/300 mL;
Temperature: 20 +/- 1°C;
period: within 14 days
Reference substance
- Reference substance:
- other: various substances (comparative study)
Results and discussion
- Preliminary study:
- No details supplied
- Test performance:
- No details supplied
% Degradation
- Parameter:
- other: BOD related to THOD
- Value:
- >= 46 - <= 57
- Sampling time:
- 5 d
- Remarks on result:
- other: 90-135 hours of incubation = 3.75 - 5.7 days, assumed to correspond to a mean of 5 days
- Details on results:
- Incubation time: 90-135 hours;
rate constant of the geometrical biodegradation: 0.044-0.069 * 1/h;
lag time: approx. 5 h
BOD5 / COD results
- Results with reference substance:
- For example:
Benzoic acid BOD/ThOD = 0.61 - 0.69 within 65 - 80 h
Butyric acid BOD/ThOD = 0.58 - 0.82 within 135 - 140 h
Any other information on results incl. tables
No details supplied
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- readily biodegradable
- Conclusions:
- In a comparative biodegradation screening applying MITI(I) test conditions, n-butanal was readily biodegradable, shown by a BOD elimination within about 4 to 6 days of 46 to 56 % in relation the added Theoretical Oxygen Demand (ThOD) of 100 mg test substance/L.
For comparison, the BOD/ThOD ratio of benzoic acid was 0.61 - 0.69 within approx. 3 days (stated 65 - 80 h), while the BOD/ThOD ratio of butyric acid was found to be 0.58 to 0.82 within approx. 6 days (stated 135 - 140 h). - Executive summary:
In a comparative biodegradation screening applying MITI(I) test conditions, n-butanal was readily biodegradable, shown by a BOD elimination within about 4 to 6 days of 46 to 56 % in relation the added Theoretical Oxygen Demand (ThOD) of 100 mg test substance/L.
For comparison, the BOD/ThOD ratio of benzoic acid was 0.61 - 0.69 within approx. 3 days (stated 65 - 80 h), while the BOD/ThOD ratio of butyric acid was found to be 0.58 to 0.82 within approx. 6 days (stated 135 - 140 h).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
