Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

chronic toxicity: inhalation
Data waiving:
study technically not feasible
Justification for data waiving:
Justification for type of information:
When in breathing atmosphere, mixing of ethyl 2-cyanoacrylate vapors with moisture (water vapors) of will therefore cause in the air fast polymerization of the substance required to be applied in the inhalation studies. Therefore, the successful competition of these in vivo studies will not be possible since the outcome will be influenced by the in-air polymerization that will lead to extremely low concentrations of the free monomers. Thus, test chemical cannot be generated as a gas, vapour, or aerosol in sufficient concentration to elicit animal toxicity in the optimal conditions of an inhalation chamber.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion