Registration Dossier

Administrative data

Endpoint:
hydrolysis
Adequacy of study:
weight of evidence
Rationale for reliability incl. deficiencies:
other: Test not experimental performed, scientifically not applicable
Data waiving:
study technically not feasible
Justification for data waiving:
other:

Data source

Materials and methods

Results and discussion

Dissipation DT50 of parent compound
Remarks on result:
other: Study technically not feasible: test substance polmerises on contact with water within seconds

Any other information on results incl. tables

Study technically not feasible: test substance polmerises on contact with water within seconds

Applicant's summary and conclusion

Conclusions:
Study technically not feasible: test substance polmerises on contact with water within seconds
Executive summary:

Tests in aqueous media with ethyl 2-cyanoacrylate with the intent to determine effective concentrations or no effect concentrations can not be performed due to technical reasons based on the chemical properties of the monomer. In presence of moisture ethyl 2-cyanoacrylate polmerises within seconds (inherent property of ethyl 2-cyanoacrylate based instant glues). Thus, very low determined monomer concentrations in water represent a non ateady state situation from which a defined effective concentration can not be derived.