Registration Dossier

Physical & Chemical properties

Water solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. certificate)
Type of method:
column elution method
Key result
Water solubility:
24 µg/L
Temp.:
20 °C
pH:
6.6

The average water solubility of the test item Ethyl 2 -cyanoacrylate determined on two flow rates (25 mL/h and 12.5 mL/h) is 0.024 mg/L (24 µg/L, 24 ppb).

Annotation:

Due to its high reactivity, ethyl 2 -cyanoacrylate immediately polymerizes when getting in contact with water. Thus, the reported value of water solubility represents the very small concentration of residual monomers which are detectable in the aqueous phase. It has to considered that the test item ethyl 2 -cyanoacrylate is stabilized with hydrochinone according to the test certicicate supplied by the sponsor.

Conclusions:
Interpretation of results: insoluble (< 0.1 mg/L)
The average water solubility of the test item Ethyl 2 -cyanoacrylate determined on two flow rates (25 mL/h and 12.5 mL/h) is 0.024 mg/L (24 µg/L, 24 ppb).
Annotation:
Due to its high reactivity, ethyl 2 -cyanoacrylate immediately polymerizes when getting in contact with water. Thus, the reported value of water solubility represents the very small concentration of residual monomers which are detectable in the aqueous phase. It has to considered that the test item ethyl 2 -cyanoacrylate is stabilized with hydrochinone according to the test certicicate supplied by the sponsor.

Description of key information

Key value for chemical safety assessment

Water solubility:
24 µg/L
at the temperature of:
20 °C

Additional information