Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-163-5 | CAS number: 92-52-4
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.017 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.17 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.002 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 10 mg/L
- Assessment factor:
- 1
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 2.69 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.269 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.528 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- PNEC oral
- PNEC value:
- 16.7 mg/kg food
- Assessment factor:
- 30
Additional information
Conclusion on classification
The classification of biphenyl is harmonized both according to the the CLP and the DSD regulation. In Annex I of the Dangerous Substance Directive 67/548/EC, biphenyl is classified as N, R50/53. In Annex VI of the CLP Regulation (EC) 1272/2008, biphenyl is classified as H410 (Aquatic Chronic 1) and also receives the GHS09 pictogram for environmental hazards.
This harmonized classification is in accordance with the experimental test results provided in this dossier. The lowest acute E/LC50 was a 48-h LC50 of 0.36 mg/L for the aquatic invertebrate Daphnia magna, which is below 1 mg/L, resulting in the R50 classification under the DSD and the redundant classification as H400 (Aquatic Acute 1) under the CLP regulation. The classification as R50/53 under the DSD regulation is based on the fact that, additionally, the substance has a log Kow >= 3 (and the experimentally derived BCF is not <= 100 L/kg). The classification as H410 under the CLP regulation is based on the fact that, additionally, the substance has a log Kow >= 4 and a BCF >= 500 L/kg. The key log Kow value for biphenyl used in the CSA is 4.008 at 25° and the key experimentally derived BCF is 1900 L/kg, which are both above the thresholds proposed by both the DSD and the CLP regulation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
