Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 202-163-5 | CAS number: 92-52-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
A Japanese modified MITI test indicated that biphenyl is readily biodegradable. Other available screening studies on both ready and inherent biodegradability support this finding.
Further, several simulation studies for biodegradation in water and water/sediment systems are available which report reliable information on the biodegradation of biphenyl. These studies indicate that biphenyl is biodegraded in water with half-lives of 2-3 days, and half-lives of 2-10 days in aerobic sediment/water systems. Biodegradation of >70% in 28 days based upon CO2 evolution also support that the substance meets the criteria for rapid degradability. Anaerobic biodegradation can be considered of limited importance for biodegradation of biphenyl in the aquatic environment. Based on the available simulation studies, it is suggested to use 3 days as key half-life for biodegradation in water and 10 days as key half-life for biodegradation in sediment for exposure calculations. These half-lives were the highest half-lives obtained in the respective studies and therefore represent a reasonable worst-case approach.
Although soil simulation studies are not required for this readily biodegradable substance, the available supporting study indicates the potential for soil microorganisms to adapt to, and fully mineralize, the biphenyl substance.
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