Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
1 400 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
Value:
7 360 mg/m³ air

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
3 271 mg/kg bw

Additional information

Oral LD50 determined in guinea pigs (Smyth 1941);

Dermal LD 50 was determined in rabbits (Carpenter 1956); the value was 3.56 mL/kg which corresponded to 3271 mg/kg (density of 0.919 g/mL at 25 °C);

Justification for classification or non-classification

Inhalative LC50 was determined in female rats 7,36 mg/l/ 8 h of exposure (Pozzani 1959); according to the "OPINION OF THE COMMITTEE FOR RISK ASSESSMENT ON A DOSSIER PROPOSING HARMONISED CLASSIFICATION AND LABELLING AT COMMUNITY LEVEL, 9 March 2011", Committee for Risk Assessment RAC, ECHA/RAC/CLH-O-0000001587-67-01/F, the substance has to be classified as Acute Tox. 3, H331;