Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 619-447-3 | CAS number: 99607-70-2
Endpoint summary
Administrative data
Description of key information
Fully reliable information on the long-term toxicity of cloquintocet-mexyl is available that can be used to derive PNEC soil.
Terrestrial toxicity studies are available concerning the effects of cloquintocet-mexyl on earthworms, soil microorganisms, plants and birds.
The substance is of low toxicity to earthworms, with a 14-day LC50 of >1000 mg/kg (dry weight) soil being reported in an OECD TG 207 study (Rufli, 1989).
A Nitrogen Transformation Test (OECD TG 216) and a Carbon Transformation Test (OECD TG 217) have been conducted under GLP (Schulze, 2013). The results are considered reliable and adequate for risk assessment. The 28-day NOEC in both tests was 1000 mg/kg soil dw, and this can be considered as a long-term result for microbial populations.
A reliable GLP and guideline compliant short-term terrestrial plant toxicity study (OECD TG 208) is available (Bramby-Gunary, 2013). Ten plant species have been tested, and the study results thus can be used to characterise long-term effects on terrestrial plants. The most sensitive species was tomato (Lycopersicon esculentum) with an EC50 of 275 mg/kg soil dw.
Cloquintocet-mexyl is of low toxicity to birds, as indicated by the long-term NOEC = 500 mg/kg obtained in two long-term toxicity studies.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
