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Environmental fate & pathways

Hydrolysis

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Description of key information

Hydrolysis of cloquintocet was determined according to the principles of OECD 111.  Cloquintocet behaves as expected for an ester. In strongly alkaline solution de-esterification is very rapid, slower at slightly alkaline pH and very slow in the range of pH 5 to 7.  The free acid (i.e. [(5-chloroquinolin-8-yl)oxy]acetic acid; CAS#: 88349-88-6; company code CGA153433) was the sole hydrolysis product found in the experiment and is therefore considered to be hydrolytically stable.

Key value for chemical safety assessment

Half-life for hydrolysis:
133.7 d
at the temperature of:
20 °C

Additional information

In hydrolysis studies cloquintocet behaves as expected for an ester. In strongly alkaline solution de-esterification is very rapid, slower at slightly alkaline pH and very slow in the range of pH 5 to 7. The following half-lives at 20°C were found (concentration of the test substance 0.4 mg/L). pH 1 = 29.8  days, pH 5 = 4.4 years, pH 7 = 133.7 days, pH 9 = 6.6 days and pH 13 = <5 minutes (25°C). The free acid (i.e. [(5-chloroquinolin-8-yl)oxy]acetic acid; CAS#: 88349-88-6; company code CGA153433) was the sole hydrolysis product found in these experiments, therefore the transformation product can be considered as hydrolytically stable.