Registration Dossier
Registration Dossier
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EC number: 209-218-2 | CAS number: 561-41-1
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- RTECS Number: PC4180000
- Year:
- 2 012
- Bibliographic source:
- RTECS (Registry of Toxic Effects of Chemical Substances):- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 1,5,1951
- Reference Type:
- review article or handbook
- Title:
- DPIM: TJK000
- Author:
- Richard J. Lewis, Sr.
- Year:
- 2 007
- Bibliographic source:
- SAX (Sax's Handbook of Dangerous Industrial Materials):- Arzneimittel-Forschung. Drug Research. 1 (1951), 5.
- Reference Type:
- other: Authoritative data base
- Title:
- GCID: 251789
- Year:
- 2 011
- Bibliographic source:
- ACToR (Aggregated Computational Toxicology Resource):- Arzneimittel-Forschung. Drug Research. Vol. 1, Pg. 5, 1951.
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Data is from RTECS, SAX & Actor
- GLP compliance:
- not specified
- Test type:
- standard acute method
Test material
- Reference substance name:
- p,p',p''-tris(dimethylamino)trityl alcohol
- EC Number:
- 207-396-6
- EC Name:
- p,p',p''-tris(dimethylamino)trityl alcohol
- Cas Number:
- 467-63-0
- IUPAC Name:
- tris[4-(dimethylamino)phenyl]methanol
- Details on test material:
- - Name of test material : p,p',p''-tris(dimethylamino)trityl alcohol
- Substance type: Organic
- Molecular formula : C25H31N3O
- Molecular weight : 389.5331
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 1 000 other: mg/kg
- Based on:
- test mat.
- Remarks on result:
- other: Details of toxic effects not reported other than lethal dose value
Applicant's summary and conclusion
- Interpretation of results:
- Toxicity Category IV
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- LD50 (Oral) for p,p',p''-tris(dimethylamino)trityl alcohol in Mouse is 1000 mg/kg suggests that the substance is toxic by the oral route.
- Executive summary:
LD50 (Oral) value of p,p',p''-tris(dimethylamino)trityl alcohol in Mouse is 1000 mg/kg suggests that the substance is toxic by the oral route.
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