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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

No inhibition of oxidation was observed in a sludge inhibition test upto 1000 mg/L 1-methylpiperazine after 30 minutes of exposure.

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
1 000 mg/L

Additional information

Three toxicity of 1 -methylpiperazine to micro-organisms tests are available. Two tests with communal activated sludge performed according to a guideline equivalent to OECD TG 209. No effect to sludge respiration was observed to 1000 mg/L nomimal during 30 minutes of exposure in these tests. One test has been performed with Pseudomonas putida according to Bringmann & Kühn (1980) which is very similar to DIN 38412. part 8. For Pseudomonas putida an EC10 has has been derived of 197.7 mg/L during 17 hours of growth. According to Table R.10-6 of the REACH guidance the test according to Bringmann & Kühn should only be used if no other tests are available. The result PNECmicro-organisms for 1-methylpiperazine will therefore be based on the observed NOEC of 1000 mg/L.