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Short-term toxicity to fish

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Description of key information

The 96h-LC50 is >995 mg/L (pH adjusted) in a 96 h static acute toxicity test with Leuciscus idus according to DIN 38412, part 15.

Key value for chemical safety assessment

LC50 for freshwater fish:
995 mg/L

Additional information

The acute toxicity of 1 -methylpiperazine to the Golden orfe, Leuciscus idus, was determined under static conditions during 96 hours according to DIN 38412, part 15. The test was performed with the following nominal test concentrations (mg/L): control, 100, 215, 464, 1000 without pH adjustment and at 1000 mg/L with pH adjustment. Without pH adjustment the initial pH at 215 mg/L was 9.3 which dropped during the first 24 hours to 8.5. The initial pH at 464 mg/L was 9.7 which dropped during the first 24 hours to 9.2. The geomean LC50 (not neutralized) was 316 mg/L and no leathality was observed at 1000 mg/L when neutralized (pH 7.7).

The active ingredient content of the test substance was 99.5%. The 96 -hour LC50 is therefore >995 mg a.i./L, i.e. the highest concentration tested based on nominal concentrations. No subleathal effects were observed. The no observed-effect concentration (NOEC) was 995 mg a.i./L, the highest concentration tested.