Registration Dossier
Registration Dossier
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EC number: 237-158-7 | CAS number: 13674-84-5
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Data were obtained in a modern GLP study and adopted in EU Risk Assessment Report (RAR).
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 2 007
Materials and methods
- Principles of method if other than guideline:
- no data
- GLP compliance:
- yes
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Tris(2-chloro-1-methylethyl) phosphate
- EC Number:
- 237-158-7
- EC Name:
- Tris(2-chloro-1-methylethyl) phosphate
- Cas Number:
- 13674-84-5
- Molecular formula:
- C9H18Cl3O4P
- IUPAC Name:
- tris(2-chloro-1-methylethyl) phosphate
Constituent 1
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 2.68
Any other information on results incl. tables
The value is log Kow = 2.68±0.36, which was obtained by the HPLC estimation method6 in a modern GLP study and the ± value is the 95% confidence limit.
Applicant's summary and conclusion
- Conclusions:
- The partition coefficient (n-octane/water) of TCPP is ca. 2.68 with a 95% confidence limit as ±0.36.
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