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Physical & Chemical properties

Partition coefficient

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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Data were obtained in a modern GLP study and adopted in EU Risk Assessment Report (RAR).

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
2007

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
yes
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
Tris(2-chloro-1-methylethyl) phosphate
EC Number:
237-158-7
EC Name:
Tris(2-chloro-1-methylethyl) phosphate
Cas Number:
13674-84-5
Molecular formula:
C9H18Cl3O4P
IUPAC Name:
tris(2-chloro-1-methylethyl) phosphate

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
2.68

Any other information on results incl. tables

The value is log Kow = 2.68±0.36, which was obtained by the HPLC estimation method6 in a modern GLP study and the ± value is the 95% confidence limit.

Applicant's summary and conclusion

Conclusions:
The partition coefficient (n-octane/water) of TCPP is ca. 2.68 with a 95% confidence limit as ±0.36.