Registration Dossier

Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only secondary literature available

Data source

Reference
Reference Type:
publication
Title:
Patty`s Industrial Hygiene and Toxicology
Author:
Clayton GD and Clayton FE
Year:
1994
Bibliographic source:
4th ed., Vol. II, Part D, 1994

Materials and methods

Type of study / information:
other: review
Test guideline
Qualifier:
no guideline followed
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Any other information on results incl. tables

Isomerization appears to decrease the oral, but increase the dermal toxicity.

Isobutyl acrylate is considered only slightly irritating.

Data from an animal study have suggested the possibility of dermal sensitivity (skin sensitization).

no further details provided

Applicant's summary and conclusion