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Short-term toxicity to aquatic invertebrates

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Description of key information

Based on data from the structural analogue n-butyl acrylate, isobutyl acrylate is considered to be acutely toxic to freshwater invertebrates.
EC50 (48 h) = 8.2 mg/L (measured), (Daphnia magna, OECD TG 202, flow through) (n-butyl acrylate)

Key value for chemical safety assessment

Additional information

In short-term tests with Daphnia magna conducted according to the EU Directive 79/831/EEC, annex V, C2 48-hour EC50 values of 9.7 and 19.8 mg/L, respectively, were found (BASF AG 1988, 1991). The given effect values were related to nominal concentrations. In these studies conducted in open test vessels, under static conditions and without analytical monitoring, the volatility of iBA was not taken into consideration. Thus, these studies are only valid with restrictions.

In addition, valid experimental data from the structural analogue n-butyl acrylate are available. An acute toxicity study with Daphnia magna (BAMM, 1990) indicated the 48-hour EC50 for n-butyl acrylate was 8.2 mg/L based on mean measured concentrations. This study followed OECD TG 202, part I using a flow-through design. Nominal exposure concentrations ranged from 1.2 to 20 mg/L and mean measured concentrations ranged from 1.4 to 17 mg/L. Complete immobilization occurred in the highest concentration (17 mg/L, measured). The NOEC was 2.4 mg/L (measured).

Since iBA is readily biodegradable and moderately volatile, only test results from studies with analytical monitoring were used for the hazard assessment for freshwater invertebrates.

In addition, a robust data set of acute studies is available from the other members of the acrylic ester category (methyl, 2-ethylhexyl, ethyl, and tert-butyl acrylate).