Registration Dossier
Registration Dossier
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EC number: 201-497-9 | CAS number: 83-73-8
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.208 mg/L
- Assessment factor:
- 50
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.104 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.021 mg/L
- Assessment factor:
- 500
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 1.362 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 985.485 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 985.485 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 470.218 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Classification for aquatic and terrestrial toxicity is not triggered based on available data, according to REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006.
Conclusion on classification
PBT Assessment
Classification of diiodohydroxyquinoline for effects in the environment
In determining the classification appropriate to diiodohydroxyquinoline, it is necessary to consider all available evidence concerning its persistence, potential to accumulate and predicted or observed environmental fate and behaviour that may present a long-term and/or delayed danger to the structure and/or functioning of aquatic ecosystems. These points are considered below.
Persistence
The substance diiodohydroxyquinoline is 50% biodegradable in water in 38 days (half-life). This value indicates that diiodohydroxyquinoline is readily biodegradable in water since the half life is less than the threshold criteria of >= 60 days (to qualify the chemical as persistent).
The substance diiodohydroxyquinoline is 50% biodegradable in water and sediment in 38 days and in 340 days respectively. This values indicates that diiodohydroxyquinoline is readily biodegradable in water while is not readily biodegradable in sediment according to the EPA criteria of >= 60 days (to qualify the chemical as persistent).
The substance diiodohydroxyquinoline is 50% biodegradable in soil in 75 days (half-life). This value indicates that diiodohydroxyquinoline is not readily biodegradable in soil since the half life is more than the threshold criteria of >= 60 days (to qualify the chemical as persistent).
Diiodohydroxyquinoline satisfies the criteria for classification as persistent (P) in sediment and soil environment.
Potential to accumulate
Predicted and measured log Kow values for diiodohydroxyquinoline is less than 4 (Log Kow = 0.602). The potential for diiodohydroxyquinoline to bioaccumulate in the tissues of organisms that inhabit aquatic or terrestrial matrices is negligible as the BCF factor for the substance is much less than 1000.
The calculated BCF of diiodohydroxyquinoline is 200 dimensionless and below the threshold of 2000.
Diiodohydroxyquinoline does not satisfy the criterion for classification as bioaccumulative (B).
The toxicity values of fish, invertebrates and algae are LC50 = 22.246 mg/L, EC50 = 12.5 mg/L and EC50 = 10.39 mg/L, respectively. However, the BCF value of diiodohydroxyquinoline reported was not >= 500 as well as the substance was found to be rapidly degradable.
Thus, diiodohydroxyquinoline does notsatisfy the environmental effects criterion for classification as toxic (T).
Thus it can be inferred that diiodohydroxyquinoline is Persistent, but not Bio-accumulative and is also not Toxic (Not PBT)
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