Registration Dossier

Classification & Labelling & PBT assessment

PBT assessment

Administrative data

PBT assessment: overall result

PBT status:
the substance is not PBT / vPvB
Justification:

PBT Assessment

Classification of diiodohydroxyquinoline for effects in the environment

 

In determining the classification appropriate to diiodohydroxyquinoline, it is necessary to consider all available evidence concerning its persistence, potential to accumulate and predicted or observed environmental fate and behaviour that may present a long-term and/or delayed danger to the structure and/or functioning of aquatic ecosystems. These points are considered below. 

 

Persistence

 

The substance diiodohydroxyquinoline is 50% biodegradable in water in 38 days (half-life). This value indicates that diiodohydroxyquinoline is readily biodegradable in water since the half life is less than the threshold criteria of >= 60 days (to qualify the chemical as persistent).

 

The substance diiodohydroxyquinoline is 50% biodegradable in water and sediment in 38 days and in 340 days respectively. This values indicates that diiodohydroxyquinoline is readily biodegradable in water while is not readily biodegradable in sediment according to the EPA criteria of >= 60 days (to qualify the chemical as persistent).

The substance diiodohydroxyquinoline is 50% biodegradable in soil in 75 days (half-life). This value indicates that diiodohydroxyquinoline is not readily biodegradable in soil since the half life is more than the threshold criteria of >= 60 days (to qualify the chemical as persistent).

 

Diiodohydroxyquinolinesatisfies the criteria for classification as persistent (P) in sediment and soil environment. 

 

Potential to accumulate

Predicted and measured log Kow values for diiodohydroxyquinoline is less than 4 (Log Kow = 0.602). The potential for diiodohydroxyquinoline to bioaccumulate in the tissues of organisms that inhabit aquatic or terrestrial matrices is negligible as the BCF factor for the substance is much less than 1000.  

 

 The calculated BCF of diiodohydroxyquinoline is 200 dimensionless and below the threshold of 2000. 

 

Diiodohydroxyquinoline does not satisfy the criterion for classification as bioaccumulative (B).

 

The toxicity values of fish, invertebrates and algae are LC50 = 22.246 mg/L, EC50 = 12.5 mg/L and EC50 = 10.39 mg/L, respectively. However, the BCF value of diiodohydroxyquinoline reported was not >= 500 as well as the substance was found to be rapidly degradable.

Thus,diiodohydroxyquinoline does notsatisfy the environmental effects criterion for classification as toxic (T).

 

Thus it can be inferred that diiodohydroxyquinoline isPersistent, but not Bio-accumulative and is also not Toxic (Not PBT)