Registration Dossier

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Using the weight of evidence approach, it can be concouded that the chemical diiodohydroxyquinoline is not likely to bio-accumulate in the aquatic and sediment environment since the bio-concentration factor (BCF) values range from 45 to 283. All the BCF values are much below the threshold of 1000 which confirm the non-bioaccumulative characteristic of the chemical. The key value of BCF has been considered to be 74 for the chemical safety asssessment.

The BCF value of diiodohydroxyquinoline is estimated to be 200. This value indicates that diiodohydroxyquinoline is not expected to bioaccumulate in the food chain because it does not exceed the bioconcentration threshold of >=1000.

Key value for chemical safety assessment

BCF (aquatic species):
74

Additional information

The various end points details used in the weight of evidence appraoch are presented below that confirm that the chemical diiodohydroxyquinoline is not bio-accumulative

Sr. No

End point name

Value

Test organism

Data Source

1

BCF 

74.166664124

Cyprinus carpio

QSAR

2

BCF 

283.645996094

Carassius auratus

QSAR

3

BCF 

200

Fish

PBT Profiler

4

BCF 

201.4

Fish

EPI Suite

5

BCF 

45.8

-

Scifinder