Registration Dossier
Registration Dossier
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EC number: 405-820-6 | CAS number: 30025-38-8
Endpoint summary
Administrative data
Description of key information
Two guideline tests to evaluate either dermal irritancy or ocular irritancy of DPGEE in the rabbit were negative by accepted EU criteria.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Justification for classification or non-classification
SKIN: The level of response of all end points was insufficient to trigger classification under directive 67/548 or regulation 1272/2008.
EYE: The level of response of all end points was insufficient to trigger classification under directive 67/548 or regulation 1272/2008. Details shown below:
Mean of measurements at 24, 48, 72 hours
|
Animal 1 |
Animal 2 |
Animal 3 |
Classification under 67/548 |
Classification under 1272/2008 |
Corneal effects |
1 |
0.3 |
0.3 |
No |
No |
Iritis |
0 |
0 |
0 |
No |
No |
Conjunctival effects |
1.7 |
1.7 |
1.0 |
No |
No |
Chemosis |
1.0 |
0.7 |
0.3 |
No |
No |
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