Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Based on the findings of a study in Daphnia magna the 48 -hr EC50 for immobilization of daphnia by DPGEE was extrapolated to be ~180 mg/L (77 - 425 95% CL). This result seems unusually low and is in fact lower than the NOEC from the reproduction (chronic) study. Also, US EPA ECOSAR software (v1.00a) estimates the 48 -hr Daphnid LC50 for dipropylene glycol monoethyl etherto be 2,297 mg/L, respectively. This is taken into account in the derivation of the short term PNEC. Together with a 96 hr LC50 value for freshwater fish at >200 mg/L (experimental) and with QSAR estimate exceeding 5000 mg/L and a NOEC >100 mg/L in aquatic single-celled algae neither the EU classification N; R50-52 nor the criteria for GHS classification Acute III are indicated. This conclusion is also reflected in the results of long-term study in freshwater fish and a study demonstrating no activity against microorganisms in sewage.