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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

48hr EC50 >150mg/l, QSAR estimate: 2297mg/l.

Key value for chemical safety assessment

Additional information

In a guideline (OECD 202) and GLP acute toxicity study (48 -hr; static), Daphnia magna were exposed to dipropylene glycol monoethyl ether at concentrations up to 150 mg/L. Based on the findings of this study the 48 -hr EC50 for immobilization of daphnia by DPGEE was extrapolated to be ~180 mg/L (77 - 425 95% CL). This result seems unusually low and is in fact lower than the NOEC from the reproduction (chronic) study; US EPA ECOSAR software (v1.00a) estimates the 48 -hr Daphnid LC50 for dipropylene glycol monoethyl etherto be 2297 mg/L, respectively. This difference should be taken into account in the choice of appropriate starting points and assessment factors for the derivation of the short term PNEC.