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Registration Dossier
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EC number: 405-820-6 | CAS number: 30025-38-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
The half-life of hydrolysis of DPGEE could not be determined. Measured degradation/loss over 5 days was 4.93% at pH 4 and 5.35% at pH7 and 0% at pH 9. Hydrolysis rate constants cannot be estimated for compounds of this type which are generally regarded as hydrolytically stable at pH ranges normally encountered in the environment.
In a valid guideline OECD 301F and GLP manometric respiration study, DPGEE was found to be readily biodegradable, with a BOD28 of 81%. Degradation of 74% was seen within the 10 day window.The substance was also assessed in a guideline inherent biodegradation study. A biodegradation rate greater than 70% (98%) in this test confirmed inherent ultimate biodegradability.
The adsorption coefficient (Koc) of ethoxypropoxy propanol is <17.8 (log10 Koc<1.25) at 40 Celsius as determined by an HPLC method. The QSAR (KOCWIN version 2.0; EPISUITE) values are supportive in that they yield a non-corrected log Koc value of 0.1507 and corrected value of -0.8534 derived from an estimated log Kow value of -1.40. These are of similar order to the experimental result. It can be concluded that DPGEE will have a low potential for adsorption to soil or sediment.
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