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EC number: 203-117-7
CAS number: 103-49-1
According to the available data from oral application. the LD50 (female) = 632 mg/kg bw was calculated and LD50(male) > 200 mg/kg bw is assumed.
Single oral application of 200 mg/kg bw diluted in polyethylene glycole
was given to male and female Wistar rats by gavage Since all females
that received 2000 mg/kg bw died no males were tested with this dose.
Signs of intoxication before death were "spasmic-jumping behaviour" ;
200 mg/kg bw was tolerated by males and females without symptoms. Body
weight development was not influenced at the dose of 200 mg/kg bw in
both sexes. Post mortem exanination was without findings in 200 mg/kg bw
males and females but females that had received 2000 mg/kg bw showed
yellow fluid in the stomach and reddened mucosa lstomach and lungs.The
approximately LD50 value for female rats was 632 mg/kg bw and the LD50
value for male rats was >200 mg/kg bw (Bayer AG.1995)
Dermal application and inhalation exposure
According to ANNEX VII Section 8.5 of Regulation (EC)1907/2006 (REACH)
acute toxicity studies with dermal application or inhalation exposure
are not required. In addition, the substance is considered to be
corrosive and is classified and labelled accordingly by
Based on the acute oral toxicity data dibenzylamine is classified and
labelled R22. harmfull if swallowed according to 67/548/EEC self
classification. According to GHS/CLP Regulation (EC)1272/2008 the
substance has to be allocatied to category 4, Hazard Statement 302
(Harmful if swallowed).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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