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Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information

Data source

Reference
Reference Type:
publication
Title:
Dibenzylamine - a novel blocker of the voltage-dependent K+ current in myocardial mouse cells
Author:
Doepner B, Koopmann R, Knopp A, Hirche HJ, Benndorf K
Year:
2001
Bibliographic source:
Naunyn-scghmiedeberg's arch Pharmacol 364,9-13

Materials and methods

Type of study / information:
in vitro investigation
Principles of method if other than guideline:
in vitro treatment of myocardial cells of mice with DBA
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Dibenzylamine
EC Number:
203-117-7
EC Name:
Dibenzylamine
Cas Number:
103-49-1
Molecular formula:
C14H15N
IUPAC Name:
dibenzylamine
Details on test material:
no further data

Results and discussion

Any other information on results incl. tables

The study show that dibenzylamine is a blocker of the voltage-dependent K-ion current in the mouse ventricular heart cells

Applicant's summary and conclusion