Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-117-7
CAS number: 103-49-1
Single oral application of 200 mg/kg bw diluted in polyethylene glycole
was given to male and female Wistar rats by gavage. Since all females
that received 2000 mg/kg bw, died, no males were tested with this dose.
Signs of intoxication before death were "spasmic-jumping behaviour" ;
200 mg/kg bw was tolerated by males and females without symptoms. Body
weight development was not influenced at the dose of 200 mg/kg bw in
both sexes. Post mortem exanination was without findings in 200 mg/kg bw
males and females but females that had received 2000 mg/kg bw, showed
yellow fluid in the stomach and reddened mucosa in stomach and lungs.The
approximately LD50 value for female rats was 632 mg/kg bw and the LD50
value for male rats was >200 mg/kg bw (Bayer AG.1995)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again