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EC number: 203-117-7
CAS number: 103-49-1
Single oral application of 200 mg/kg bw diluted in polyethylene glycole
was given to male and female Wistar rats by gavage. Since all females
that received 2000 mg/kg bw, died, no males were tested with this dose.
Signs of intoxication before death were "spasmic-jumping behaviour" ;
200 mg/kg bw was tolerated by males and females without symptoms. Body
weight development was not influenced at the dose of 200 mg/kg bw in
both sexes. Post mortem exanination was without findings in 200 mg/kg bw
males and females but females that had received 2000 mg/kg bw, showed
yellow fluid in the stomach and reddened mucosa in stomach and lungs.The
approximately LD50 value for female rats was 632 mg/kg bw and the LD50
value for male rats was >200 mg/kg bw (Bayer AG.1995)
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