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EC number: 242-362-4
CAS number: 18479-58-8
Results of the OECD 301B ready biodegradation test indicate that the
test item is readily biodegradable: 72% degradation after 28 days.
According to the REACH regulation, it was not necessary to conduct the
following tests as the test item was determined to be readily
- Hydrolysis test
- Biodegradation in water and sediment: simulation test
- Biodegradation in soil
Adsorption/desorption: the adsorption coefficient of dihydromyrcenol was
determined using the HPLC method. Under the conditions of study, the
adsorption coefficient of the test item was 177.83 (log Koc = 2.25).
This finding suggests that the test item will show limited binding to
soil or sediment particulates.
Photodegradation in air: removal from the atmosphere by reaction in
sunlight is predicted to be rapid (half-life due to reaction with
atmospheric OH radicals or ozone 3.449 hours or 22.92 hours
respectively, QSAR estimates)
Although the experimentally determined Log Kow of the test item is
slightly greater than 3.0, low BCF (64.8
(L/kg ww or dimensionless) estimated by the BCFBAF v3.00 module of
EPISuite v4.0) and
rapid biotransformation in fish are predicted by application of the
widely accepted EPISuite QSAR model to the test item. The prediction of
rapid biotransformation is supported by analogy to mammalian metabolism
data. Together, these results lead to low concern for possible
addition a similar BCF value can be derived using the BCF model
mentioned in REACH guidance R.18.104.22.168, this results in a BCF value of
115 l/kg wwt. This
somewhat higher value does not allow for metabolic transformation, which
is modelled in the EPISuite QSAR calculation (and mammalian
toxicokinetic data in this dossier support a prediction of such
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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