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EC number: 242-362-4
CAS number: 18479-58-8
Observations on cultures: After 72 hours, no abnormalities were observed
in the control or test cultures at test material concentrations of 6.25,
12.5, 25 and 50 mg/l. At 100 mg/l, few intact cells were observed.
In a 72 -hour acute toxicity study, the cultures of Desmosdesmus
subspicatus were exposed to the test item at nominal
concentrations, confirmed by analysis, of 0, 6.25, 12.5, 25, 50 and
100 mg/l in accordance with OECD guideline 201. The NOEC, ErC50 and
EbC50 values were 25, 80 and 65 mg/l, respectively.
At 72 hours, no abnormalities of cultures with test material
concentrations of 6.25, 12.5, 25, and 50 mg/l test were observed. At
100 mg/l were few intact cells observed.
This toxicity study is classified as acceptable and satisfies
the guideline requirements for the acute toxicity to algae study.
Test Organism: Desmodesmus subspicatus
Test Type: static
72-hr ErC50: 80 mg/l
72 -hr EbC50: 65 mg/l 95% C.I.: 56 to
72 -hr NOEC: 25 mg/l
One key study has been identified as adequate to assess the toxicity of the test item to aquatic algae. This study followed the OECD 201 guideline and was GLP-compliant.
The test item gave 72h ErC50 and EbC50 values of 80 and 65 mg/l
respectively in the key algal growth inhibition study.
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