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EC number: 203-347-8
CAS number: 105-95-3
the analytical problems observed in the experimental ecotoxicological
studies, a weight of evidence approach with QSAR estimations has been
considered more appropriate to assess the aquatic toxicity of the
substance than basing the results uniquely upon the exisiting aquatic
dataset. Further investigation is ongoing on this difficult substance in
order to determine whether instability or analytical issues accounted
for the loss observed in older test samples.
reliable endpoint values, geometric means between the experimental
results (based on initial measured concentrations) and the QSAR
v1.11 QSAR model available from the U.S. EPA) were determined for three
trophic levels: Algae,
Invertebrates and Fish. The results are summarised in the table below.
Flag / reliability
Reference in IUCLID / comments
Weight of evidence approach
activated sewage sludge
30min: 12400 mg/L
Toxicity to microorganisms, Caspers, 1996, RS, K
data available, fish seems to be the most sensitive species in acute
exposure with an estimated 96h-LC50 at 1.87 mg/L.
chronic studies are available. The choice to perform long-term studies
will be defined after further investigation on this difficult substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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