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EC number: 203-347-8
CAS number: 105-95-3
Environmental fate and pathways
Further investigation is ongoing on this
difficult substance in order to determine whether instability or
analytical issues account for the rapid loss observed under
ecotoxicological test conditions.
the analytical problems observed in the experimental ecotoxicological
studies, a weight of evidence approach using both in vivo and
QSAR estimations has been used to assess the aquatic toxicity of the
substance. Further investigation is ongoing on this difficult substance
in order to determine whether instability or analytical issues account
for the rapid loss observed under ecotoxicological test conditions.
reliable endpoint values, geometric means between the experimental
results (based on initial measured concentrations) and the QSAR
v1.11 QSAR model available from the U.S. EPA) were determined for three
trophic levels: Algae,
Invertebrates and Fish.
data available, fish seems to be the most sensitive species in acute
exposure with an estimated 96h-LC50 at 1.87 mg/L.
chronic studies are available. The choice to perform long-term studies
will be defined after further investigation on this difficult substance.
Based on a conservative estimation from
Chesar, the chemical safety assessment of the substance indicates no
need to investigate terrestrial testing. For this reason, terrestrial
toxicity studies are scientifically unjustified.
1 mg/L < E(L)C50<
10 mg/L; readily biodegradable; log Kow = 4.3 but estimated BCF = 319.3 L/kg.
according to the Annex VI of the Directive 67/548/EEC: The
substance is classified as N, R51/53 for the environment.
according to the Annex VI of the Regulation (EC) No 1272/2008 (CLP): According
to the 2nd ATP, the substance is not classified
for the environment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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