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EC number: 220-778-7
CAS number: 2896-70-0
A GLP study was performed in accordance with OECD guideline 405, to
assess the effect of 2,2,6,6,-tetramethyl-4 -oxopiperindinooxy when
administered to the eye.
A single dose of 0.1 ml of test material was applied
to the right eye of three New Zealand white rabbits. Assessment of the
animals was made at 1 hour, 24, 48 and 72 hours after treatment.
The test material produced a maximum group mean score of 8.7 and was
classified as a mild irritant (Class 4 on a 1 to 8 scale) to the rabbit
eye using a modified Kay and Calandra classification system.
No classification with respect to eye irritancy is required.
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