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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

A GLP study was performed to assess the effect of 2,2,6,6,-tetramethyl-4 -oxopiperidinooxy on the reproduction of Daphnia Magna over a period of 21 days. The study was performed in accordance with OECD guideline 202.
The 14 and 21-day EC50(immobilisation) values for the parental Daphnia generation were calculated to be 20 and 13 mg ai/l with 85% confidence limits of 17 – 23 mg ai/l and 7.4 - 23 mg ai/l respectively.
The 21-day EC50(reproduction) is considered to be 7.4 mg ai/l.
All values quoted are based on nominal concentrations.
The ‘No Observed Effect Concentration’ (NOEC) is considered to be 2.3 mg ai/l.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
2.3 mg/L

Additional information

A reliability rating of 1 was assigned to the key study, according to the criteria of Klimisch, 1997 as the study was conducted in accordance with recognised guidelines and GLP.