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EC number: 925-259-5
CAS number: 140921-24-0
The results indicate that the test substance does not have a significant irritation potential on skin and eye. Thus, the test substance can be regarded as non irritating to the skin and eye.
The irritant/corrosive potential of the test
substance was studied on the skin and eye of the rabbit in accordance
with OECD guideline 404 and 405. Whilst considering OECD Interpretation
Guides results were interpreted in conjunction with the nature,
intensity and reversibility of responses observed. The irritation was
scored accordig to Draize after 1 h, 24 h, 48 h, 72 h and 7 d.
- Regarding skin irrition: All three animals
showed irritation indices of 0 for both erythema/eschar formation and
- Regarding eye irritation: All three
animals showed irritation indices of 0 for both cornea, iris conjuctivae
and epithelial defects. Irritation indices for aqueous humour and
discharge were 2 and 3, respectively after 1 hour. But these signs were
fully reversible after 24 h.
The results indicate that the test substance
does not have a significant irritation potential on skin and eye. Thus,
the test substance can be regarded as non irritating to the skin and
In this skin and eye irritation study using
rabbits the test substance was reported to be non irritating.
on the results the test substance does not have to be classified as
irritating to skin and/or eye according to EU Directive 67/548/EEC (DSD)
and Regulation (EC) No 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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