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EC number: -
CAS number: -
No specific study was performed on the absorption, distribution,
metabolism and/or excretion (ADME) of WS400123, a complex mixture of
components. Low to moderate absorption and systemic availability of
WS400123 or some of its components after oral exposure has been
concluded from small, non-adverse changes observed in some blood
parameters in the subacute and subchronic toxicity studies in rats.
Dermal absorption has been concluded from the sensitization response
attained in a Local Lymph Node Assay (LLNA) in mice at non-irritating
test concentrations of WS400123.
Exposure of humans to WS400123 by the inhalation route is
unlikely, because of its very low vapour pressure (1 x 10-3Pa
at 25°C), its decomposition at high temperature without boiling (above
ca. 150°C) and because it is a highly viscous liquid.
All available study results gave no indication regarding the
metabolic pathway, distribution or excretion of WS400123.
Bioaccumulation was not investigated, but in view of its Log10Pow<
+1, WS400123 is not considered to have a bioaccumulation potential.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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