Registration Dossier

Administrative data

Endpoint:
in vivo mammalian germ cell study: cytogenicity / chromosome aberration
Remarks:
Type of genotoxicity: chromosome aberration
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Authoritative data base
Title:
Danish QSAR study for CAS No.: 561-41-1
Author:
Danish EPA Model
Year:
2012
Bibliographic source:
QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:- DK-EPA

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Modelling database
Principles of method if other than guideline:
Rodent, Dom. Lethal (Rodent Dominant Lethal Test): Multicase model
GLP compliance:
no
Type of assay:
rodent dominant lethal assay

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material : 4,4'-bis(dimethylamino)-4''-(methylamino)trityl alcohol
- Substance type: Organic
- Molecular formula : C24H29N3O

- Molecular weight : 375.5066

Test animals

Species:
other: Rodent
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
other: No data

Results and discussion

Test results
Sex:
not specified
Genotoxicity:
not specified
Toxicity:
no effects
Vehicle controls validity:
not specified
Negative controls validity:
not specified
Positive controls validity:
not specified

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): negative
4,4'-bis(dimethylamino)-4''-(methylamino)trityl alcohol gives negative result in Rodent Dominant Lethal Test
Executive summary:

4,4'-bis(dimethylamino)-4''-(methylamino)trityl alcohol gives negative result in Rodent Dominant Lethal Test