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Environmental fate & pathways

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Description of key information

Bioaccumulation: aquatic/sediments:

Using BCFBAF Program (v3.00) model of EPI suite (2018) the estimated bio concentration factor (BCF) for test chemical is 352.7 L/kg wet-wt at 25 deg. c which does not exceed the bioconcentration threshold of 2000. Therefore it is concluded that test chemical  is nonbioaccumulative in food chain.

Additional information

Bioaccumulation: aquatic/sediments:

Predicted data studies and experimental study have been done for biaccumulation in aquatic organisms endpoint of test chemical and its read across chemical and their results are summarized below

The first prediction was done by using BCFBAF Program (v3.00) model of EPI suite (2018) the estimated bio concentration factor (BCF) for test chemical is 352.7 L/kg wet-wt at 25 deg. c which does not exceed the bioconcentration threshold of 2000. Therefore it is concluded that test chemical  is nonbioaccumulative in food chain.

Another prediction was done by using Bio-concentration Factor (v12.1.0.50374) module the Bio-concentration Factor at range pH 0-14  of the test chemical was estimated to be  in range 1.0- 888 dimensionless. These values indicate that the test chemicalis non-bioaccumulative in aquatic organisms as this value does not exceed 2000 criteria.

Next study was experimental study reviewed from authoritative database (HSDB) in this the Bioaccumulation test was conducted for estimating the bioconcentration factor (BCF) of test chemical.The bioconcentration factor was determined to be 500 dimesionless, from an estimated log Pow of 8.69 and a regression derived equation. This suggests that the potential for bioconcentration of test substance in aquatic organisms is low.

By considering all the studies mentioned above BCF value of test chemical is expected to be in range of 352 -888 dimensionless therefore it is concluded that test chemical is non bioaccumulative in nature.