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Ecotoxicological information

Long-term toxicity to fish

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Reference
Endpoint:
adult fish: sub(lethal) effects
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
Data is from computational model developed by USEPA
Qualifier:
according to
Guideline:
other: Modeling database
Principles of method if other than guideline:
Long term toxicity of test chemical were determined on the basis of predicted mortality of fish.
GLP compliance:
no
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
other: Fish
Test type:
flow-through
Water media type:
freshwater
Total exposure duration:
28 d
Reference substance (positive control):
no
Key result
Duration:
28 d
Dose descriptor:
NOEC
Effect conc.:
0.293 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: Other details not known
Validity criteria fulfilled:
no
Conclusions:
On the basis of no effects observed on fish in flow-through freshwater system, the NOEC value for the substance is estimated to be 0.293 mg/l for fish for 28 days of exposure duration.
Executive summary:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on fish was predicted for test substance. On the basis of effects observed in a flow through freshwater system, the NOEC value for the test substance is estimated to be 0.293 mg/l for fish after 28 days of exposure. As no effect were observed thus chemical cannot be classify in toxic category

Description of key information

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on fish was predicted for test substance. On the basis of effects observed in a flow through freshwater system, the NOEC value for the test substance is estimated to be 0.293 mg/l for fish after 28 days of exposure. As no effect were observed thus chemical cannot be classify in toxic category.

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater fish:
0.293 mg/L

Additional information

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on fish was predicted for test substance. On the basis of effects observed in a flow through freshwater system, the NOEC value for the test substance is estimated to be 0.293 mg/l for fish after 28 days of exposure. As no effect were observed thus chemical cannot be classify in toxic category.