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EC number: 201-297-1
CAS number: 80-62-6
The ability of macrophages obtained from the peritoneal
cavity of mice to phagocyte Staphylococcus aureus was
inhibited by 0.5% MMA in the culture medium. Human
heparinised blood was incubated with concentrations of 0.5%,
1.25%, and 2.5% MMA for 15 min. The number of leucocytes
was reduced at a concentration of 2.5% MMA, no viable cells
were detected by the trypane blue method, at 1.25% the
number of viable leucocytes was reduced to about 50%.
Phagocytic polymorphonuclear neutrophils were damaged to a
greater extent than lymphocytes. Erythrocytes and platelets
were completely lysed at 2.5% MMA.
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