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Physical & Chemical properties

Partition coefficient

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Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Principles of method if other than guideline:
other (measured): equilibration: shake flask; analytical method: GC
GLP compliance:
not specified
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water
Analytical method:
gas chromatography
Type:
log Pow
Partition coefficient:
1.38
Temp.:
20 °C
pH:
ca. 7
Remarks on result:
other: The test originally was performed at room temperature and without a pH-value mentioned. Therefor we assumed a temperature of 20 °C. The test substance has no effect on the pH-value therefor it is assumed to be ca. pH: 7.0.

Study was performed without adjustment of pH value.

Conclusions:
Using a valid scientific method the partition coefficient of the substance was 1.38 at 20C.
Executive summary:

Using a valid scientific method the partition coefficient of the substance was 1.38 at 20C.

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
no
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
Methyl methacrylate from Ineos Acrylics, Batch No. Acrylics 98/15, purity: > 99 %
Analytical method:
high-performance liquid chromatography
Type:
log Pow
Partition coefficient:
1.32
Temp.:
20 °C
pH:
ca. 7

Description of key information

Two experimental studies for the determination of octanol-water partition coefficient are available according shake flask method with with nearly similar results: Log Kow 1.38 and log Kow 1.32. The highest value is used as key value.

Key value for chemical safety assessment

Log Kow (Log Pow):
1.38
at the temperature of:
20 °C

Additional information