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EC number: 215-572-9
CAS number: 1332-65-6
The freshwater sediment effect records include 62 high quality single-species chronic NOEC/L(E) C10 values from 6 different different sediment- dwelling species of relevance to setting the freshwater aerobic sediment PNEC in a WOE approach.Considering the importance of bio-availability for reducing the intra-species variability, the data- base includes supportive information related to the development/validation of the sediment organic carbon normalization. The NOECS and OC normalization model are used for the aerobic sediment PNEC derivation. Information in support of the protective effect of sediment sulphides is useful to the risk characterization.
Freshwater sediment NOECS
The high quality records retained for
the PNEC derivation of copper under the Existing Substances
Regulation (TCNES) and Biocidal Products regulations (Technical
meetings) have been included in the IUCLID data-base.
Tests that were considered as not-reliable for the PNEC derivations
have NOT been included in the IUCLID records but have been
summarized in the copper RA report (2008).
quality chronic NOEC/(L(E) C10 values are available for 6 different
sediment- dwelling organisms. the amphipodsHyalella aztecaandGammarus
pulex, the oligochaetesTubifex tubifexandLumbriculus
variegatus, the insectChironomus ripariusand the insectHexagenia.
The Individual NOEC values range between
18.3 mg/kg dry weight and >3,158 mg/kg (min-max value). Large
intra-species variability are observed due to variations in organic
carbon (OC) content and acid volatile sulphide (AVS) content of the
sediments (De Schamphelaere et al.,2005). Normalization of the
NOECs/(L(E) C10 for OC was demonstrated. Normalization
of the effects data for AVS was not possible and therefore only
NOEC/(L(E) C10 values generated under conditions that represent
“aerobic” conditions (Low AVS) were considered as adequate for the
PNEC derivation. Effects data from studies with AVS concentration
lower than the 10th percentile of the AVS concentration (i. e. 0.77
mmol/kg dry weight) were thus retained. Using this exclusion rule,
the original dataset containing 106 NOEC values was reduced to a
trimmed data set of 62 NOEC values for copper.
The data base includes additional
information in support of the importance if AVS binding in the field
(Boothman et al., 2001) and demonstrating the lesser sensitivity of algae
in the biofilm compared to free living algae(Barranguet
et al., 2000)and the applicability
of long term benthic studies to the life cycle (Pasteris et al.,
The records related to effects
observed in freshwater mesocosm studies (multi-species, covering
water and sediment) are included in section 6.6. (additional
ecotoxicological information). Copper threshold values from three
high quality mesocosm studies, representing lotic and lentic systems
Sediment PNEC derivation
For the freshwater PNEC derivation, a weight of evidence
approach is applied , using the information from the different
environmental compartments: (1) using the freshwater PNEC in an
equilibrium partitioning approach; (2) using the high quality
freshwater sediment NOECS and (3) comparison with soil NOECS
For the estuarine and marine PNEC derivations, the equilibrium
partitioning approach is used
Summaries on the sediment PNEC
derivations are provides as attachments
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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