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Toxicological information

Specific investigations: other studies

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Administrative data

Endpoint:
cytotoxicity
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Test procedure in accordance with generally accepted scientific standards and described in sufficient detail.

Data source

Reference
Title:
Cytotoxic effects of acrylates and methacrylates: Relationships of monomer structures and cytotoxicity
Author:
Yoshii E.
Year:
1997
Bibliographic source:
J. Biomed. Mater. Res. 37(4): 517 - 524

Materials and methods

Principles of method if other than guideline:
3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H tetrazorium bromide (MTT) assay
GLP compliance:
not specified
Type of method:
in vitro

Test material

Reference
Name:
Unnamed

Results and discussion

Details on results:
The Cytotoxic effect of MMA on the relative cell viability of HeLa S3 cells was IC50: 89.89 mmol/L (50 % depression of MTT-formazan production).

Applicant's summary and conclusion