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Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information

Data source

Reference
Reference Type:
publication
Title:
Toxizitaet von Methylmethacrylat auf das Endothel der Hornhaut in vitro
Author:
Boehnke M., Quaye N., Burk R., Draeger J.
Year:
1985
Bibliographic source:
Fortschr. Ophthalmol. 82: 418-421 (1985)

Materials and methods

Type of study / information:
other: in vitro effects of corneal cells
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed

Results and discussion

Any other information on results incl. tables

Cell damage ranging from vacuolic degenerative changes to necrosis of endothelial cell layers was observed.   The severity of the damage increased with increasing incubation time and increasing monomer
concentration.

Applicant's summary and conclusion