Registration Dossier
Registration Dossier
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EC number: 201-166-9 | CAS number: 79-00-5
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Additional information
There are no available data.
Effects on developmental toxicity
Description of key information
The only study report was related to a developmental screening assay. This study report was found to be not reliable, according to the lack of information concerning test results.
Additional information
In a screening developmental toxicity study, the chemical was administered by gavage to mice on days 8 through 12 of gestation at the only dose of 350 mg/kg bw/day (Seidenberg et al., 1987). Any changes including teratogenicity or embryo/fetal viability, and/or postnatal growth and viability were observed. Therefore, the NOAEL for developmental toxicity was considered to be 350 mg/kg bw/day.
Substance induced negative results in the screening teratology study (Chernoff/Kavlock assay). No further assays for teratology assessment were conducted with substance.
Justification for classification or non-classification
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
