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Short-term toxicity to aquatic invertebrates

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Description of key information

With high probability acutely not harmful to aquatic invertebrates

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
108.82 mg/L

Additional information

The acute toxicity of MIPA (CAS 78-96-6) to aquatic invertebrates was determined in a static freshwater test conducted according to Directive 79/831/EEC, Annex V, Part C, using Daphnia magna as test species (BASF AG, 1992). The reported 48 -h EC50 of 108.8 mg/L indicates the test substance to be with high probability acutely not harmful to daphnids. The test substance solutions were not neutralized.


The study was conducted without analytical monitoring. However, the stability of MIPA in the test medium is considered to be stable due to the high water solubility (miscible at any ratio; see IUCLID chapter 4.8), the low vapour pressure (63 Pa at 25 °C; see IUCLID chapter 4.6) and the low Henry's law constant (HLC: 4.95E-5 Pa*m3/mol; calculated; HENRYWIN v3.20, EPISuite v4.11) of the substance.