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EC number: 485-320-2 | CAS number: 221667-31-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Phototransformation in soil
Administrative data
Link to relevant study record(s)
- Endpoint:
- phototransformation in soil
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 14 Sep 2004 - 24 Mar 2005
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EPA Guideline Subdivision N 161-3 (Photodegradation Studies on Soil)
- Qualifier:
- according to guideline
- Guideline:
- other: Commission Directive 95/36/EC amending Council Directive 91/414/EEC, 1995-07-14
- Qualifier:
- according to guideline
- Guideline:
- other: SETAC, Procedures for Assessing the Environmental Fate and Ecotoxicity of Pesticides, March 1995
- Qualifier:
- according to guideline
- Guideline:
- other: Canada PMRA DACO Number 8.2.3.3.1
- GLP compliance:
- yes (incl. QA statement)
- Radiolabelling:
- yes
- Analytical monitoring:
- yes
- Analytical method:
- high-performance liquid chromatography
- Details on soil:
- COLLECTION AND STORAGE
- Geographic location: Latitude N 35° 29.303' and Longitude: W 078° 02.421'
City: Pikeville
County: Wayne
State: North Carolina
Country: USA
PROPERTIES
- Soil classification system and year: USDA (Fine-loamy, siliceous, sub active, thermic Aquic Paleudults)
- Soil texture. Sandy loam
- % sand: 76
- % silt: 16
- % clay: 8
- pH: pH in water (1:1, Soil: Water): 6.0 , pH in IN KC1: 5.1, pH in saturated paste: 6.0
- Organic carbon (%): 0.7%
- CEC (meq/100 g): 3.9
- Initial moisture at 1/3 atm (%):
- Water holding capacity: 9.9 for 1/10 bar(g/100g), 6.7 for 1/3 bar(g/100g) and 2.6 for 15 bar (g/100g)
- Bulk density (g/cm3): 1.31
- Initial microbial biomass/microbial population (unit): 92 (methoxybenzoyl label) and 92 (sulfonylbenzamide label)
PREPARATION OF SOIL
- Condition of soil: Sieved
- Air dried / fresh: Air dried - Light source:
- Xenon lamp
- Light spectrum: wavelength in nm:
- >= 290 - <= 750
- Relative light intensity:
- 683
- Details on light source:
- - Emission wavelength spectrum: 290-750 nm
- Filters used and their purpose: <290 nm cut-off filter- Suprax
- Relative light intensity based on intensity of sunlight: 58% of the light intensity of the artificial light source falls in the range
of 300-800 nm, which is the absorption region of interest of natural sunlight in the environment. - Details on test conditions:
- TEST SYSTEM
- Type, material and volume of test apparatus or thin layers: 4-cm diameter quartz glass vessels fitted with rubber septa
- Volume of test solution used/treatment: 21 µL (methoxybenzoyl) 33 µL (sulfonylbenzamide)
- Method of application: 25 or 50 µL syringe, applied evenly as drops onto soil surface
- Co-solvent evaporated: yes, solvent allowed to air dry 3-5 minutes in laboratory hood
- Details of traps for volatile, if any: A static closed system was used. At sampling, volatiles were purged through closed system with nitrogen gas into
volatile traps.. Volatiles were purged at each sampling interval (except day 0) through 2 M KOH, ethylene glycol, and 1 M sulfuric acid.
- Indication of test material adsorbing to the walls of test apparatus: No
REPLICATION
- No. of replicates (dark): Duplicate
- No. of replicates (irradiated): Duplicate
MAINTENANCE OF TEST CONDITIONS SPECIFIED UNDER "DURATION"
- Moisture maintenance method: Not necessary, negligible moisture loss (< 0.4%) - Duration:
- 9 d
- % Moisture:
- 75
- Temp.:
- 20 °C
- Initial conc. measured:
- 1.07 other: mg a.i./kg soil for (methoxybenzoyl)
- Duration:
- 9 d
- % Moisture:
- 75
- Temp.:
- 20 °C
- Initial conc. measured:
- 1.08 other: mg a.i./kg soil for (sulfonylbenzamide)
- Reference substance:
- yes
- Remarks:
- three non-radiolabelled substances
- Dark controls:
- yes
- Remarks:
- 14C-dark controls
- DT50:
- >= 20.8 - <= 39.6 d
- Test condition:
- Methoxybenzoyl Label
- DT50:
- 19.1 d
- Test condition:
- Sulfonylbenzamide Label
- Transformation products:
- no
- Validity criteria fulfilled:
- not applicable
Reference
The first-order half-life values of AE 0001789 in the methoxybenzoyl dark and irradiated samples were 39.6 days and 20.8 experimental days, respectively. The phototransformation rate constant, obtained by subtraction (kirradiated- kdark), resulted in a photo transformation half-life (DT50) of 43.8 experimental days, and a DT90 of 145.5 experimental days. These are equivalent to a DT50 of 144 and a DT90 of 478 solar days in, Phoenix, Arizona. The first-order half-life value of AE 0001789 in the sulfonylbenzamide irradiated samples was 19.1 experimental days. The half-life value was not calculated for the dark samples due to minimal degradation. Therefore, the calculated photo transformation DT50 was the same as the irradiated samples, 19.1 experimental days, and the DT90 was 63.6 experimental days. These are equivalent to a DT50 of 62.7 and a DT90 of 209 solar days in, Phoenix, Arizona, respectively.
The degradation rates for AE 0001789 in the dark samples are significantly lower than those observed in the aerobic soil metabolism studies, which used,Pikeville, NC, soil. Such difference may be attributed to a) the comparably low microbial biomass (attributed to low soil moisture content) measured for the present batch of soil, and b) an unfavorable ratio of the application solvent (ACN, potentially harmful to soil microbes) needed for solubility reasons and the relatively small amount of soil used in a soil photolysis test system (33 and 21 µL ACN per 3 g soil). However, such reduced soil microbial viability does not impair the objective of testing abiotic surface photolytic degradation processes.
The kinetic results are summarized in the tables below:
Half-lives under laboratory conditions (DT50) in experimental days:
Methoxybenzoyl Label:
Test System |
Half-life (days) |
First order |
R² |
DT50 (days) |
DT90 (days) |
Regression equation (Ct = Co * e-kt) |
|||||
Dark |
39.6 |
Ct=101.1*e (-0.0750t) |
0.7565 |
39.6 |
131.6 |
Irradiated |
20.8 |
Ct = 98.88 * e (-0.3332t) |
0.9507 |
20.8 |
69.1 |
Phototransformation Rate |
|
k = 0.01582 |
|
43.8 |
145.5 |
Sulfonylbenzamide Label:
Test System |
Half-life (days) |
First order |
R² |
DT50 (days) |
DT90 (days) |
Regression equation (Ct = Co * e-kt) |
|||||
Dark |
NC* |
Ct=95.96*e (-0.00039t) |
0.0023 |
NC |
NC |
Irradiated |
19.1 |
Ct = 93.81*e (-0.03620t) |
0.8168 |
19.1 |
63.6 |
Phototransformation Rate |
|
k = 0.03620 |
|
19.1 |
63.6 |
**NC = not calculated (no degradation)
Description of key information
DT50 19.1 – 43.8 days (EPA 161-3)
Key value for chemical safety assessment
- Half-life in soil:
- 43.8 d
Additional information
In the available GLP study (M-254211-01-1), the photolytic route and rate of degradation of Cyprosulfamide was studied on one sandy loam soil under exposure to simulated sunlight and aerobic conditions in the laboratory for 9 days at 20 °C, 75% of 1/3 bar water holding capacity and at an initial concentration of 1.04 and 1.07 µg a.i./g of soil. The study was performed according to EPA 161-3. The photolytic degradation half-live (DT50) for Cyprosulfamide in soil was estimated to 19.1 – 43.8 days.
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