Registration Dossier
Registration Dossier
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EC number: 485-320-2 | CAS number: 221667-31-8
Endpoint summary
Administrative data
Description of key information
Additional information
Cyprosulfamide is not readily biodegradable under the conditions of the manometric respirometry test (30 % after 28d; OECD 301 F).
Degradation half-lives in total water/sediment systems ranged from 144.6 - 335.4 days (recalculated to 12 °C) under aerobic conditions and from 442.8 - 452.8 days (recalculated to 12 °C) under anaerobic conditions. Aerobic mineralization reached a maximum of 19.2% applied radioactivity (AR) after 132 days. No anaerobic mineralization was observed after 155 days.
The substance degrades in soil under aerobic laboratory conditions with half-lives of 4.9 - 22.5 days (recalculated to 12 °C) and a mineralization to 14CO2 of 43 - 61.9% AR after 120 days.
Cyprosulfamide is hydrolytically stable at pH 4, 7 and 9 and a temperature of 25°C.
The substance is expected to be dissociated under environmental pH values of 5-9 due to a measured pKa of 4.2 (OECD 112).
The log Pow of the substance at pH 4 is 1.77 and decreases with increasing pH. At pH 7 a log Pow of -0.80 and at pH 9 a log Pow of -1.81 was determined. Therefore, the substance has a low potential for bioaccumulation.
The log Koc values determined for the substance in seven different soils at neutral pH are 0.9 - 1.88 L/kg (OECD 106). Accordingly, the potential to adsorb to soil and suspended particles is low.
In irradiated solution the substance degraded with a half-life of 3.5 -5.0 days under study conditions, equivalent to a calculated half-life of about 6 days in natural sunlight. The soil photolysis is a minor degradation pathway; the equivalent mean DT50 data for moderate light intensity is 63 - 144 days.
The substance has a vapour pressure of < 0.00001 Pa at 20 °C with a calculated Henry Law Constant of 1.80E-9 Pa x m³/mole (25 °C). Evaporation and subsequent tranport through the atmosphere are not expected. A rapid photodregradation by reaction with photogenerated hydroxyl radicals with a DT50 of 4 hours was calculated for Cyprosulfamide. Thus, air is not a likely route of environmental contamination and accumulation and subsequent deposition of the substance is not expected.
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