Registration Dossier
Registration Dossier
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EC number: 485-320-2 | CAS number: 221667-31-8
Dissociation constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- dissociation constant
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 112 (Dissociation Constants in Water)
- Deviations:
- no
- Principles of method if other than guideline:
- spectrophotometric method
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- HESSISCHES MINISTERIUM FÜR UMWELT, LANDWIRTSCHAFT UND FORSTEN, Wiesbaden, Germany
- Dissociating properties:
- yes
- pKa:
- 4.2
- Temp.:
- 20 °C
- Remarks on result:
- other: room temperature. SD = 0.07
Reference
Experiment |
pKa value |
SD |
A |
4.24 |
0.05 |
B |
4.20 |
0.06 |
C |
4.10 |
0.11 |
Mean |
4.18 |
0.07 |
The dissociation constant of the test item was: pKa = 4.2 (SD = 0.07)
Description of key information
pKa = 4.2 (SD = 0.07) at room temperature, pH values between 0.92 to 12.47
(OECD 112, spectrophotometric method)
Key value for chemical safety assessment
- pKa at 20°C:
- 4.2
Additional information
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