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EC number: 442-390-9
CAS number: 40573-09-9
The acute oral toxicity of the test article was determined in Sprague
Dawley rats. The study was conducted in compliance with OECD GLP (1999).
The test method was based on OECD Guideline 423 (1996) and EC Method B.1
(1996). Rats (3/sex) were administered a single dose of 2,000 mg/kg body
weight of undiluted test article by oral gavage. Body weights (Days 1,
8, and 15) and clinical signs (twice daily) were recorded. No mortality
occurred during the study, and body weight gain was not impaired. On
study Day 1, stilted gait was observed in 1 animal and a squatting
posture in 2 animals. No other clinical signs were observed in any other
animals at any time points. Based on the results of the study, the oral
LD50 of the test article is > 2000 mg/kg body weight.
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