Registration Dossier
Registration Dossier
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EC number: 442-390-9 | CAS number: 40573-09-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
An acute oral toxicity study has been conducted on MV31. The result of the study was:
Acute oral toxicity is greater than 2000 mg/kg when tested according to OECD 423.
Key value for chemical safety assessment
Additional information
The acute oral toxicity of the test article was determined in Sprague Dawley rats. The study was conducted in compliance with OECD GLP (1999). The test method was based on OECD Guideline 423 (1996) and EC Method B.1 (1996). Rats (3/sex) were administered a single dose of 2000 mg/kg body weight of undiluted test article by oral gavage. Body weights (Days 1, 8, and 15) and clinical signs (twice daily) were recorded. No moratlity occurred during the study, and body weight gain was not impaired. On study Day 1, stilted gait was observed in 1 animal and a squatting posture in 2 animals. No other clinical signs were observed in any other animals at any time points. Based on the results of the study, the oral LD50 of the test article is > 2000 mg/kg body weight.
Justification for classification or non-classification
MV31 does not meet the DSD or CLP criteria for classification by the oral route.
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